Of all the world's cities, perhaps none is so defined by its as Florence. This small Italian city on the of the Arno River gave birth to the Renaissance and changed the way we see the world. In Florence, art is everywhere. The Uffizi Gallery houses the world's most important collection of Renaissance art, including works by Leonardo da Vinci, Michelangelo, Botticelli, and Raphael. The city's Duomo, or cathedral, is a of Gothic architecture and an iconic red-tiled dome designed by Brunelleschi. Florence's streets are like an open-air museum, with sculptures and fountains at every turn. It's a city that has artists for centuries and continues to do so today.